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protein-classification

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Assignments Completed during BIO543:Big Data Mining in Healthcare Course in IIITD during Winter 2025 Semester. Professor: Gajendra P.S. Raghava

  • Updated Apr 29, 2025
  • Jupyter Notebook

A machine learning pipeline for eukaryotic signal peptide prediction — from UniProtKB data collection to a CNN-LSTM classifier on ESM-2 embeddings. Implements and benchmarks three methods: a von Heijne PSWM baseline, an SVM with biochemical features, and a deep learning model (F1=0.962, ROC-AUC=0.998).

  • Updated Apr 23, 2026
  • Jupyter Notebook

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