Reduce memory usage by avoiding issubclass(Schema)#703
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issubclass() calls against Schema triggered ABCMeta.__subclasscheck__ calls which adds to an internal weaksets, _abc_cache, _abc_negative_cache
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addresses #665
issubclass()calls against Schema classes were triggering ABCMeta.subclasscheck calls which adds to an internal weaksets, _abc_cache, _abc_negative_cache