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Mitchell R. Vollger and others added 29 commits October 29, 2025 15:14
…ng, also need to turn that into a real peak file
…ng, also need to turn that into a real peak file
Co-authored-by: Mitchell R. Vollger <mvollger@gmai.com>
…ng, also need to turn that into a real peak file
…ng, also need to turn that into a real peak file
…s and incoperating the underlying FIRE elements so I can find the natural peak start and end
Add new `mock-fire` CLI subcommand that generates mock BAM files with
FIRE elements from a BED file. Each interval becomes a FIRE element,
with the 4th column grouping intervals into the same mock read.

Bug fixes:
- Fix score calculation overflow when quality=255 by capping at 253
  and limiting max score to 100
- Fix peak merging to select representative peak by highest score
  instead of lowest FDR, ensuring the peak_max reflects the position
  with most FIRE coverage
- Add hidden --min-fire-coverage parameter to call-peaks for testing
  with low-coverage data

New files:
- src/cli/mock_fire_opts.rs
- src/subcommands/mock_fire.rs
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2 participants