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Three figures from Braun data analysis#29

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sgosline merged 5 commits intomasterfrom
origin/add_scripts
Mar 13, 2026
Merged

Three figures from Braun data analysis#29
sgosline merged 5 commits intomasterfrom
origin/add_scripts

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@CamiloPosso
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Adding three figure markdowns

  • ksea_heatmap.Rmd: Uses KSEApp to estimate the Kinase activity in 5 contrasts, then plots a heatmap of the results.
  • beataml_subtypes_pca.Rmd: Plots the pca of the common features between the beataml210 cohort and the Braun dataset, coloring by subtype.
  • deconvolution_pca.Rmd: Shows the pca of the estimated cell composition of the Braun + BeatAML data. Also plots individual boxplots of the cell type values for the Braun data.

ksea_heatmap.Rmd - Uses KSEApp to estimate the Kinase activity in 5 contrasts, then plots a heatmap of the results.
beataml_subtypes_pca.Rmd - Plots the pca of the common features between the beataml210 cohort and the Braun dataset, coloring by subtype.
deconvolution_pca.Rmd - Shows the pca of the estimated cell composition of the Braun + BeatAML data. Also plots individual boxplots of the cell type values for the Braun data.
@CamiloPosso CamiloPosso changed the title Origin/add scripts Three figures from Braun analysis Jan 29, 2026
@CamiloPosso CamiloPosso changed the title Three figures from Braun analysis Three figures from Braun data analysis Jan 29, 2026
Small path error when sourcing, added source calls to the Rmds to fix this.
@sgosline
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sgosline commented Feb 5, 2026

Can you create a readme that summarizes the analysis, describes where the data reside, and cites the preprint? I made some minor changes to install less common packages as well. Synapse link should point here: https://www.synapse.org/Synapse:syn64021143

Added a comment or two
Also added install for less common packages.
@sgosline sgosline self-requested a review March 13, 2026 16:52
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In general the code is in good shape (though could use a bit more comments). The markdowns require a lot more description: what are you trying to show, and why? generally there is a scientific question underlying the analysis that will be answered.

@sgosline sgosline merged commit 3cf3b48 into master Mar 13, 2026
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2 participants